- UFC 3 (Xbox One)
- UFC Personal Trainer: The Ultimate Fitness System (Xbox 360)
- UFL (Xbox Series X|S)
- UglyDolls: An Imperfect Adventure (Xbox One)
- Ultimate Chicken Horse (Xbox One)
- Ultimate Marvel Vs. Capcom 3 (Xbox One)
- Ultimate Racing 2D (Xbox One)
- Ultimate Sheep Raccoon (Xbox Series X|S)
- Ultra Hat Dimension (Xbox One)
- Ultra Street Fighter IV (Xbox 360)
- UltraGoodness 2 (Xbox Series X|S)
- Ultratron (Xbox One)
- Unbox (Xbox One)
- Uncanny Valley (Xbox One)
- Uncharted Tides: Port Royal (Xbox One Version) (Xbox One)
- Undead Blackout (Xbox One)
- Undead Horde (Xbox One)
- Under Defeat HD: Deluxe Edition (Xbox 360)
- Under the Waves (Xbox Series X|S)
- Underhero (Xbox One)
- UnderMine (Xbox One)
- Undertale (Xbox One)
- Underworld Ascendant (Xbox One)
- Undisputed (Xbox Series X|S)
- Unepic (Xbox One)
- UnExplored - Unlocked Edition (Xbox One)
- Unicorn Overlord (Xbox Series X|S)
- Unknown 9: Awakening (Xbox Series X|S)
- Unknown Fate (Xbox One)
- Unmechanical: Extended (Xbox One)
- Unmechanical: Extended Edition (Xbox One)
- Unnamed Fiasco (Xbox One)
- Uno (Xbox One)
- Unpacking (Xbox Series X|S)
- Unravel (Xbox One)
- Unravel Two (Xbox One)
- Unruly Heroes (Xbox One)
- Unsighted (Xbox One)
- Unsouled (Xbox One)
- Untitled Goose Game (Xbox One)
- Unturned (Xbox One)
- Use Your Words (Xbox One)